Synthesis, Characterization, Antimicrobial and Antimalarial Activities of 5-((2- phenylacetoxy) carbonyl)-1H-pyrazole-3-carboxylic Acid and its Ce(III), Pr(III) and Nd(III) Complexes

In the past decade, lanthanoid coordination chemistry was one of most focused areas research due to their wide applications as catalyst, magnetism, luminescence and diagnostic tools in biological studies. this study, novel pyrazole; 5-((2-phenylacetoxy) carbonyl)-1Hpyrazole-3-carboxylic acid derivative its complexes are designed tested for potential antimicrobial antimalarial activities. The binuclear ligand bridge were obtained by interaction with lanthanide salts. compounds characterized 1H 13C nuclear magnetic resonance (NMR) spectroscopy, UltravioletVisible Fourier Transform infrared (FT-IR) Mass spectrometry (MS), Elemental analysis Magnetic susceptibility measurements. vitro assay done Agar well diffusion method vivo studies performed based on Peter’s method. results analysed using way variance (ANOVA). antiparasitic effects these found be dose-dependent they showed greater at higher doses.&nbsp